Meeting programme

MONDAY JANUARY 27th 2020

  • 12:30    Welcome lunch and registration
  • 14:00    Official opening
  • 14:20    Prof. Matthew Francis – Protein-Protein Coupling Using Enzymatic Oxidative Coupling Reactions
  • 15:00    Dr Sébastien Gouin – From the design of an antibacterial glycoconjugate to the development of a chemoselective bioconjugation method for tyrosine.
  • 15:20    Dr Elisabetta Mileo – Nitroxide-based spin tags coupled to EPR spectroscopy: investigation of protein structural dynamics in vitro and inside cells
  • 15:40    Ruben Tomás – Controlling Synthetic Polymer Ligation to Metabolically Labelled Cellular Interfaces to Introduce Non-native Functionality
  • 15:50    Coffee Break + Poster session 1
  • 16:30    Dr Vladimir Torbeev – Making order out of disordered proteins
  • 17:00    Dr Olivier Sénèque – How chemoselective ligations make the design of peptide-based responsive luminescent probes easier
  • 17:30    Dr Somnath Mukherjee – Impact of site-specific non-enzymatic posttranslational modification on the structure-activity attributes of human Heat Shock Protein 27 (Hsp27)
  • 17:50    Dr Elisabeth Garanger – Expanding the toolbox of chemoselective modifications of protein-like polymers at methionyl residues
  • 18:00    Coffee Break
  • 18:30     Public lecture in French: Dr Denis Servent – Venins, du poison au médicament

TUESDAY JANUARY 28th 2020

  • 08:45    Welcome coffee
  • 09:00    Prof. Lutz Ackermann – C─H Activation as an Transformative Tool for Late-stage Diversification of Biomolecules
  • 09:40    Dr Samir Messaoudi – Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation
  • 10:00    Rebecca Schäfer – The Bioorthogonal Isonitrile-Chlorooxime Ligation
  • 10:10    Coffee Break + Poster session 2
  • 11:10    Dr Didier Boturyn – Design of RGD peptide conjugates for imaging and therapeutic applications
  • 11:50    Prof. Beat Fierz – Synthetic and single-molecule exploration of the dynamic chromatin landscape
  • 12:20    Lunch
  • 13:30    Dr Frédéric Taran – Recent advances in fast, bioorthogonal ligation reactions
  • 14:10    Dr Cyrille Sabot – From organic methodology to the development of chemoselective ligations
  • 14:40    Dr Laia Miret Casals – Furan crosslink technology: from in vitro analysis of peptide-protein interactions to GPCR-ligand interactions on live cells
  • 15:00    Dr Pierre Milbeo – Development of Novel Thiol-ene Mediated Peptide Ligation Strategies
  • 15:20    Dr Gosuke Hayashi – Chemical synthesis of histone proteins through novel ligation strategies
  • 15:40    Coffee Break + Poster session 3
  • 16:20    Prof. Carlo Unverzagt – Merging Chemistries for the Synthesis and Evaluation of Homogenous Glycoproteins
  • 17:00   Dr Kevin Neumann – Cyanosulfurylide as a protecting group for carboxylic acid during peptide synthesis
  • 17:20    Prof. Wenshe Liu – Phage-Encoded Noncanonical Amino Acids for Drug Discovery
  • 17:40    Guided visit of Orléans town center

WEDNESDAY JANUARY 29th 2020

  • 08:45    Welcome coffee
  • 09:00    Dr Oleg Melnyk – A cysteine selenosulfide redox switch for protein chemical synthesis
  • 09:40    Dr Fabienne Burlina – Extending chemical ligation for the synthesis of proteins: Application to NEMO ubiquitylation
  • 10:10   Dr Marina Rubini – Semisynthetic approaches for studying post-translational modifications
  • 10:30    Coffee Break
  • 11:00    Dr Barbara Bernardim – Title to be announced
  • 11:20    Prof. Alexander Dömling – Multicomponent reaction chemistry: From novel small molecules to automated nano chemistry to stapled peptides
  • 12:00    Official closing
  • 12:10     Farewell cocktail