Scientific Programme

October 21st, 2019 (afternoon)

1 pm – 1:40 pm : registration, coffee

1:40 pm – 1:50 pm : welcome address

1:50 pm – 2:30 pm : Helma Wennemers
“The Many Faces of Proline”

2:30 pm – 2:50 pm : Igor Komarov
Natural peptides endued with “unnatural” structure and functions (case studies)

2:50 pm – 3:10 pm : Lucile Fischer
Helical aromatic oligoamide foldamers for protein surface recognition

3:10 pm – 3:30 pm : Susanne Huhmann
Towards fluorinated, peptide-based HIV-1 fusion inhibitors

3:30 pm – 3:50 pm : Marcin Drag
Hybrid Combinatorial Substrate Library with unnatural amino acids in design of specific and active probes for proteolytic enzymes


3:50 pm – 4:20 pm : soft drinks


4:20 pm – 5:00 pm : Dafydd Jones
Making proteins do unnatural things with unnatural amino acids: from non-native-PTM to nanotechnology”

5:00 pm – 5:20 pm : Julien Pytkowicz
Non Canonical Trifluoromethylated Amino Acids: Efficient Tools to Modify Peptides Conformation and Hydrophobicity

5:20 pm – 5:40 pm : Arnaud Martel
Asymmetric Synthesis of R and S d-Valerolactamic Quaternary Amino Acids as Chiral b-Turn Inducers

5:40 pm – 6:00 pm : Samir Messaoudi
“”Tag and modify” strategy for the Pd-catalyzed Thioglycoconjugation of peptides

6:00 pm – 6:40 pm : Muriel Gondry
Cyclodipeptide synthase-dependent pathways: an efficient tool to incorporate non-canonical amino acids into  2,5-diketopiperazines

6 : 40 pm – 8:00 pm : poster session / cocktail


8:00 pm – 10:00 pm : diner



October 22nd, 2019 (morning)

8:30 am – 9:10 am : Irene Coin
Genetically encoded chemical tools for GPCR studies”

9:10 am – 9:30 am : Shixin Ye
Photosensitive tyrosine analogues unravel site-dependent phosphorylation in TrkA initiated MAPK/ERK signaling”

9:30 am – 9:50 am : Annemieke Madder
3-(2-Furyl)alanine as a versatile and ROS triggerable amino acid for peptide and protein crosslinking and labeling”

9:50 am – 10:10 am : Dmytro Dziuba
Diazirine-based unnatural amino acids as chemical tools for studying RNA-protein interactions”

10:10 am – 10:30 am : Robert Quast
Improving the accuracy of smFRET measurements through site-specific protein labeling using two distinct non-canonical amino acids with orthogonal reactivity “


10:30 am – 11:00 am : coffee break


11:00 am – 11:40 am : Thomas Sakmar
Using Genetic Code Expansion Technology to Probe the Functionality of Cryptic Ligand-Binding Pockets in GPCRs”

11:40 am – 12:00 am : Carlos Elena-Real
Site-specific incorporation of isotopically labeled amino acids to study homorepeat proteins at high resolution

12:00 am – 12:20 am : Davy Sinnaeve
Fluorinated prolines to investigate protein-protein interactions

12:20 am – 12:40 am : Lionel Imbert
In vitro specific labelling of proteins: A powerful tool to study challenging targets using NMR spectroscopy


12:40 am – 12:50 am : concluding remarks