Chemistry of amino acids, peptides and proteins

Chemistry of amino acids, peptides and proteins

Team LeaderLabLocationMain KeywordSecond KeywordWebsiteGFPP membership
Dr Oleg MelnykMiniproteins & Therapeutics Team (MINT team)
CNRS UMR9017 & Inserm U1019
LilleChemistry of amino acids, peptides, and proteinsPeptide therapeutics and clinical applications
March 13, 2024

GFPP teams, by research themes

If you want your team to be considered as a GFPP team, just click on the button below to access the form for applying.

 

Why apply to/Advantages of a GFPP membership:
1/ access to a network of researchers and develop collaborations
2/ identify expertise on peptide science, from synthesis to applications
3/ share knowlegde and know-how
4/ find experts to take on new challenges
5/ gain recognition and visibility for our skills and expertise


Interactive table for finding GFPP teams by research themes

Chemistry of amino acids, peptides and proteins

Peptide natural products

Peptide biology

 

Structural studies of peptides & self-assemblies

Emerging peptide-based technologies

Peptide therapeutics & clinical applications

Peptide mimetics, peptoids and peptide nucleic acids

Peptide conjugates (sugar, lipid, nucleic acid, drug)

Peptide prodrugs

Peptide targeting & delivery

Proteomics and peptide bioinformatics

Peptide materials

Peptide computational studies & artificial intelligence

Peptides & green approaches

GFPP teams. Interactive map & table

 


GFPP teams

If you want your team to be considered as a GFPP team, just click on the button below to access the form and apply.

 

Why apply to/Advantages of a GFPP membership:
1/ access to a network of researchers and develop collaborations
2/ identify expertise on peptide science, from synthesis to applications
3/ share knowlegde and know-how
4/ find experts to take on new challenges
5/ gain recognition and visibility for our skills and expertise

Clicking on a specific region of the map will display all GFPP teams located in that area below the map.


GFPP teams, by location

(might not work on smart phones, please use an office computer)

ncAA2024 Registration

ncAA2024 Key Dates

Please note that registration at the “The ncAAs-2024 : Noncanonical amino acids (ncAAs)” meeting will be limited to the first 150 attendees

June 7th, 2024: Deadline for oral communication submission

June 28th, 2024: Deadline for poster submission.

June 28th, 2024: End of registration.

Registration types Registration
Students / PhDs/ Postdocs 60 €
Academics 100 €
Private company delegates 150 €

Registration fees include:

  • Access to all scientific sessions
  • Abstract book ?
  • Coffee breaks
  • Welcome evening ?
  • Lunch ?
  • Gala buffet ?

Registration ncAA2024

Registration to ncAA 2024



    ex: UMR7200, U62, etc








    Program

    Program

    ncAAs 2024 Invited Speakers

    Invited Speakers

    Prof Jason CHIN

    University of Cambridge, UK

    https://www2.mrc-lmb.cam.ac.uk/ccsb/jason-chin/

    Jason Chin is a Programme Leader at the Medical Research Council Laboratory of Molecular Biology (MRCLMB), where he is also Head of the Centre for Chemical & Synthetic Biology (CCSB). He is a Professor of Chemistry & Chemical Biology at the University of Cambridge, and holds a joint appointment at the University of Cambridge Department of Chemistry. He is also a fellow in Natural Sciences at Trinity College, Cambridge.

    Jason is a native of the UK. He was an undergraduate at Oxford University, where he worked with Professor John Sutherland on Cephalosporin biosynthesis. He obtained his PhD as a Fulbright awardee from Yale University, working with Professor Alanna Schepartz. He was a Damon Runyon Fellow at The Scripps Research Institute with Professor Peter Schultz where he developed the first approaches to systematically expand the genetic code of eukaryotic cells and pioneered approaches, that are now widely used, for defining protein interactions by genetically encoding photocrosslinking amino acids.

    Jason’s work has been recognized by a number of awards, including: the Francis Crick Prize (Royal Society), the Corday Morgan Prize (Royal Society of Chemistry), European Molecular Biology Organization’s (EMBO) Gold Medal, Louis-Jeantet Young Investigator Career Award, Sackler International Prize in the Physical Science. He is in the European Inventors Hall of Fame, a member of EMBO, a Fellow of the Academy of Medical Sciences, and a Fellow of The Royal Society. Jason’s early work provided a foundation for Ambrx and he is the founder and CSO of Constructive Bio. He is also a non-executive director at the UK Government’s Department of Science, Innovation and Technology.


    Prof Benjamin DAVIS

    Sugars and Proteins

    University of Oxford, UK

    Website

    Ben Davis got his B.A. (1993) and D.Phil. (1996) from the University of Oxford. During this time he learnt the beauty of carbohydrate chemistry under the supervision of Professor George Fleet. He then spent two years as a postdoctoral fellow in the laboratory of Professor Bryan Jones at the University of Toronto, exploring protein chemistry and biocatalysis.

    In 1998 he returned to the U.K. to take up a lectureship at the University of Durham. In the autumn of 2001 he moved to the Dyson Perrins Laboratory, University of Oxford and received a fellowship at Pembroke College, Oxford. He was promoted to Full Professor in 2005.

    His group’s research centres on the chemical understanding and exploitation of biomolecular function (Synthetic Biology, Chemical Biology and Chemical Medicine), with an emphasis on carbohydrates and proteins. In particular, the group’s interests encompass synthesis and methodology; target biomolecule synthesis; inhibitor/probe/substrate design; biocatalysis; enzyme & biomolecule mechanism; biosynthetic pathway determination; protein engineering; drug delivery; molecular biology; structural biology; cell biology; glycobiology; molecular imaging and in vivo biology.

    Ben was elected a Fellow of the Royal Society in 2015, and the Academy of Medical Sciences in 2019. He is Science Director of the Next Generation Chemistry theme and became the Interim Director for the Franklin in November 2023.


    Prof Klara HLOUCHOVA (Charles University, Czech Republic)

    Why these 20 amino acids and could life function with a different set?

    Klara Hlouchova is assistant professor and group leader in the department of cell biology of Charles University in Prague. She graduated with a MSc degree in biochemistry in 2005 and then started her PhD research at the Institute of Organic Chemistry and Biochemistry (IOCB) in Prague under the guidance of Prof. Jan Konvalinka.

    She then moved to the University of Colorado Boulder, USA under the Cooperative Institute for Research in Environmental Sciences Postdoctoral Fellowship to pursuer her research on molecular evolution of enzymes and metabolic pathways in the laboratory of Prof. Shelley Copley.

    Since 2017, Klara has been developing her independent research at Charles University in Prague where she became assistant professor in 2019. Her research topics focus on the design and characterization of proteins/protein libraries from canonical/reduced/unnatural amino acids by methods of synthetic biology. Her research group is interested in various aspects of protein evolution ranging from astrobiology and origins of life to protein engineering and synthetic life.

    (http://khlab.org/)


    Prof Beate KOKSCH

    Construction and degradation of fluorinated biopolymers

    Freie Universität, Germany

    Website

    Prof. Dr. Beate Koksch studied chemistry at the Technical University Merseburg and University Leipzig in Germany, where she completed a PhD in biochemistry. Following a DFG postdoctoral research fellowship at The Scripps Research Institute in La Jolla, California, she started her independent career at University of Leipzig in 2000. In 2004, she assumed her position as Organic and Natural Product Chemistry Professor at the Freie Universität Berlin. Her research program at FU Berlin focuses on peptide and protein engineering with applications to current problems in biomedicine, biotechnology, and materials science. One key aspect that her research group has devoted its efforts to over the past 20 years is expanding the toolkit of building blocks to include fluorinated aliphatic amino acids to improve the pharmacokinetic and physicochemical profiles of peptide/protein-based drugs and materials, respectively. Advances in these areas rely on the combination of various scientific disciplines such as organic chemistry, biochemistry, molecular biology, biophysics, material sciences, analytics, and theory, and her group is collaborating with several groups at the Freie Universität Berlin, Max-Planck-Institutions and research goups nationally and internationally. Professor Koksch is a of the Max-Bergmann-Kreis for the Advancement of Peptide Chemistry, the GDCh division of Fluorine Chemists, elected board member of the European Peptide Society as well as serves as Editorial Advisory Board member of several scientific journals and. Professor Koksch had been  Director of the DFG Graduate Program “Fluorine as a Key Elements” that was running in Berlin from 2009-2018. She has received the 2021 ACS Award for Creativity in Fluorine Chemistry.


    Prof Norbert SEWALD

    Bielefeld University, Germany

    https://sewaldlab.de

    Norbert Sewald is a professor of Organic, Bioorganic Chemistry, and Chemical Biology at Bielefeld University. He studied chemistry at the Technical University of Munich. In 1991, he obtained his Ph.D. thesis in Organic Chemistry with Prof. Burger. From 1991 to 1992, he worked as a postdoctoral researcher in the group of Prof. J. E. Baldwin at the Dyson Perrins Laboratory at Oxford University. In 1998, he obtained his habilitation at the University of Leipzig. Since 1999, he has been full professor at Bielefeld University.

    Prof. Sewald’s research group focuses on non-canonical amino acids and peptidomimetics in peptides and proteins. Special emphasis is placed on enzymatic halogenation, late-stage modification of peptides and peptidomimetics, and tumor targeting.

    ncAAs 2024 Venue

    ncAAs 2024 venue

    The ncAAs-2024 “Noncanonical amino acids (ncAAs): Tools for Biological and Biophysical Investigations” meeting will be held on October 14th and 15th, 2024 in Paris.

    This event will be held in Campus des Cordeliers (Sorbonne Université, 15 rue de l’Ecole de Médecine, Paris 6e) in the centre of Paris very close to the Latin Quarter situated on the left bank of the Seine.

     

    Paris is accessible by train or plane (Roissy Charles de Gaulle Airport, Orly Airport, Beauvais Airport).

    The Campus de Cordeliers is accessible by car and public transportation:

    Métro: Lines 4 or 10 (Odéon station)

    RER B : Saint-Michel or Luxembourg stations

    RER C : Saint-Michel station

    Bus: Lines 38, 27, 58 (Rue des Ecoles or Odéon stop) and lines 63 et 86 (Cluny stop)

    Parking (charged) is available close to the Campus Parking (entrance from rue de l’école de médecine)

    ncAAs 2024 at a glance

    Time to the meeting

    The 2nd edition of the “Noncanonical amino acids (ncAAs): Tools for Biological and Biophysical Investigations” meeting will be held on October 14th and 15th, 2024 in Paris. The conference is jointly organized by Sorbonne Université and CY Cergy-Paris Université and the GFPP (Groupe Français des Peptides et Protéines – French Peptides Society) will partner with this event.

    This event will be held in Campus des Cordeliers (15 rue de l’Ecole de Médecine, Paris 6e). It will bring together up to 150 participants, chemists and biologists from public and private sectors. The scientific program will span the interface between chemistry and biology, with the participation of prestigious international speakers.
    A considerable part of the congress program will be dedicated to communications presented by young scientists: about 15 oral presentations will be selected from submitted abstracts, and ample space will be available for poster communications. The proceedings of the congress will be published in the form of an abstract book, and partners who agree to sponsor this congress will be acknowledged upfront in this book, as well as on the ncAA website.

    All participants will have to register online. For any enquiry, please contact us:

     

    Meeting venue
    Meeting program
    Invited speakers
    Abstract submission & guidelines
    Registration
    Very soon

     

    Looking forward to seeing you in Paris!

    The organizing committee

    Topics covered by the meeting:
    • Cell Free Expression
    • Amber codon
    • Noncanonical amino acid synthesis
    • Expanded genetic code
    • Auxotrophic strains
    • Protein labeling
    • tRNA synthetase engineering
    • Single molecule imaging
    • Photo-crosslinking

    Organizing committee:
    Dr Grégory CHAUME (CY Cergy Paris Université, FRANCE)
    Dr Maud LARREGOLA (CY Cergy Paris Université, FRANCE)
    Prof Olivier LEQUIN (Sorbonne Université, FRANCE)
    Dr Emeric MICLET (Sorbonne Université, FRANCE)
    Dr Pierre MILBEO (CY Cergy Paris Université, FRANCE)
    Dr Chiara ZANATO (CY Cergy Paris Université, FRANCE)

    ncAAs 2024 Abstract submission & Guidelines

    ncAAs 2024 Abstract submission & Guidelines

    On the basis of the abstracts submitted, the scientific committee will select 15 short presentations (15 min, question includes), giving preference to young researchers (PhD students or PostDocs).

    An ample space will be available for poster communications. Please note that we do not print the posters, but racks & pins will be provided for up to A0 sizes, in portrait format.

    The proceedings of the congress will be published in the form of an abstract book


    Abstract submission

     

    Please, use the following template to prepare your abstract:

    Template for abstracts ncAAs 2024

    Please name the file as follows: ncAAs 2024_Abstract_YourName

     




       

      Previous board committees

      Composition of previous GFPP committees

       

      2022-2023*
      Name Surname Specific mission
      Cantel Sonia Newsletter
      Chaume Grégory Vice-president
      Faure Sophie President
      Garanger Elisabeth Secretary/social networks
      Giraud Matthieu Social networks
      Inguimbert Nicolas
      Landon Céline Broadcast list
      Lequin Olivier Treasurer
      Melnyk Oleg French EPS representative, Webmaster
      Milazzo Isabelle
      Sénèque Olivier
      Stefan Loic Webteam
      Tonali Nicolo Webteam

      * With the assistance of Frédéric Bihel to the webteam.

       

      2019-2022
      Name Surname Specific mission
      Aucagne Vincent
      Bihel Fréderic Webmaster
      Cantel Sonia President
      Cavelier Florine French EPS representative
      Chaume Grégory Secretary
      Faure Sophie Newsletter, Broadcast list
      Garanger Elisabeth
      Giraud Matthieu
      Inguimbert Nicolas Vice-president
      Lequin Olivier Treasurer
      Milazzo Isabelle
      Ochsenbein Françoise
      Sénèque Olivier

       

      2017-2019
      Name Surname Specific mission
      Aitken David Vice-president
      Aucagne Vincent President
      Ayoub Mimoun
      Bihel Fréderic Webmaster
      Cantel Sonia
      Cavelier Florine French EPS representative
      Chaume Grégory Secretary
      Colau Arthur Treasurer
      Couve-Bonnaire Samuel
      Faure Sophie
      Garanger Elisabeth
      Miclet Emeric
      Ochsenbein Françoise
      Sénèque Olivier

      CPP2024 Abstract submission & Guidelines

      Cell-Penetrating Peptides: Next generation delivery systems
      On the basis of the abstracts submitted, the scientific committee will select 19 short presentations (10 min + 2 min questions), giving preference to young researchers (PhD students or PostDocs).
      In addition, the scientific committee will also select 20 flash presentations (2 slides with 3 minutes of presentation time) to attract participants to the poster session that will take place directly afterward.

      Please note that we do not print the posters, but racks & pins will be provided for up to A0 sizes, in portrait format.


      CPP2024 Key Dates

      April 30rd, 2024 Deadline for oral communication submission and early registration
      May 5th, 2024 Deadline for poster submission
      May 5th, 2024 End of registration

       


      Abstract submission

       

      Please, use the following template to prepare your abstract:

      Template for abstracts CPP2024

      Please name the file as follows: CPP2024_Abstract_YourName

       





        We thank our sponsors

        GFPP membership for teams

        GFPP membership for teams

          The aim of this form is to allow research groups, research teams or research units to apply for a GFPP membership FOR FREE.

          Why apply to/Advantages of a GFPP membership:
          1/ access to a network of researchers and develop collaborations
          2/ identify expertise on peptide science, from synthesis to applications
          3/ share knowlegde and know-how
          4/ find experts to take on new challenges
          5/ gain recognition and visibility for our skills and expertise

          By submitting the form, the applicant agrees to see part or all of the information provided published on the GFPP website.

          The submitting person must be the head of the research structure (group, team, research unit).

          Part or all the information provided by filling the form will be published on the GFPP website.

          (*): Required fields.

          The leader of the research structure


          Prof.Dr.

          The lab



          Your research activity

          Select in the drop-down menu below the field that characterizes your activity
          First choice

          Select in the drop-down menu below the field that characterizes your activity
          Second choice



           

           

          CPP2024 Program

           

          Cell-Penetrating Peptides: Next generation delivery systems

          Program & guidelines for presentations

           

          (updated April 3, 2024)


          We thank our sponsors

          CPP2024 Venue

           

          Cell-Penetrating Peptides: Next generation delivery systems

          CPP2024 Venue

          Montpellier is close to the Mediterranean Sea, in the south-east of France, in the Hérault department, whose territory is defined as an amphitheater open to the sea, bordered by the Cévennes to the north-east and the Haut-Languedoc to the north-west.

          Montpellier is accessible by:

          – Plane: Airport Montpellier Méditerrannée

          – Train: Station Saint-Roch (in the city center) or Station Montpellier Sud de France (outside of the city)

          Thanks to 4 lines of tramway, ample bus services (line 6, 7, 8, 11, 12, 16), taxis, you can go anywhere your heart desires in and around Montpellier.

           

          The CPP-2024 conference on “Cell-Penetrating peptides: Next generation delivery systems” will be held on June 10-12, 2024, in the Botanical Institute of Montpellier.

          With its four million samples of rare plants kept on six floors, this herbarium is unique in France. Now a property of the University of Montpellier, the collection began with Charles Flahaut in 1889 and then enriched. The oldest pieces may be those of the Chirac collection, the 17th century, or the famous Delile herbarium brought back to Egypt’s campaign in 1798…”

          The Botanical Institute of Montpellier is in the west of Montpellier close to the historic center and is situated at the following address: 163 Rue Auguste Broussonnet, 34090 Montpellier.

           

          Access via tramway 1 (Station Albert 1er – Saint-Charles) or tramway 4 (Station Albert 1er -Cathedrale)

           

          Different hotels and accommodations are available in the near. Here a selection of hotels that you can contact:

          Many other hotels of different categories are also available in the city center (near the Place de la Comédie), located only 5 tramway stations (12 min transportation) from the Conference Hall.


          We thank our sponsors

          CPP2024 Registration

           

          Cell-Penetrating Peptides: Next generation delivery systems

          CPP2024 Key Dates

          Please note that registration at the “Cell-Penetrating Peptides: Next generation delivery systems” conference will be limited to the first 200 attendees

          April 30rd, 2024 Deadline for oral communication submission and early registration
          May 5th, 2024 Deadline for poster submission
          May 5th, 2024 End of registration

           

          Registration fees inclue VAT (10%)
          Registration types Fees
          Students / PhDs 165 €
          Academics / PostDocs 275 €
          Private company delegates 330 €

           

          Registration fees include:

          • Access to all scientific sessions
          • Abstract book
          • Coffee breaks
          • Welcome evening (10 June 2024)
          • Lunch (11 June 2024)
          • Gala buffet (11 June 2024)
          Registration site

           


          We thank our sponsors

          CPP2024 Invited Speakers

          Cell-Penetrating Peptides: Next generation delivery systems

          CPP2024 Invited Speakers

           

          Steven F. Dowdy, Ph.D., is Professor of Cellular & Molecular Medicine at UCSD School of Medicine. He received his PhD in Molecular Genetics from the University of California Irvine with Prof. Eric Stanbridge and was a postdoctoral fellow with Prof. Bob Weinberg at the Whitehead Institute, MIT. In 1994, Dr. Dowdy became an Investigator at the Howard Hughes Medical Institute and an Assistant Professor at Washington University School of Medicine. He moved his lab to UCSD in 2001. His early research focused on understanding the molecular basis of G1 cell cycle deregulation during oncogenesis by RB, p16, and cyclin:CDK complexes, determining that cyclin D:CDK4 complexes activated RB by mono-phosphorylation. Concurrently, his research also focused on the intracellular delivery of macromolecular therapeutics, including siRNAs, ASOs, peptides, and proteins. His recent work over the last 10+ years has focused on developing new chemistry to tackle the rate-limiting endosomal escape problem that plagues the intracellular delivery of all macromolecular therapeutics. Dr. Dowdy has been advising biotech and pharmaceutical companies for 35 years, he currently sits on five biotech science advisory boards and is co-founder of Clear Skies Bio. He was an elected board member of the Oligonucleotide Therapeutics Society (OTS) and remains on the OTS science advisory board.


          Sarah Jones is a Reader in Pharmacology and a member of the Molecular Pharmacology Research Group at the University of Wolverhampton. For the past 20 years, Sarah’s research has focused on Cell Penetrating Peptides (CPPs) and she has played a major role in the development of bioactive CPPs, bioportides. This has resulted in a paradigm shift from the use of CPPs merely as inert vectors, to their applicability and therapeutic utility as modulators of intracellular protein-protein interactions. Identification of these novel cryptic CPPs within key signaling proteins has resulted in scientific publications regarding the utility of bioportide technology in apoptosis, angiogenesis, and Parkinson’s disease pathophysiology. In 2013, the Molecular Pharmacology Group reported that CPPs readily enter spermatozoa. This development precipitated the subsequent identification of bioportides capable of penetrating human sperm cells to modulate the activities of intracellular proteins that control calcium signaling, motility, and fertilization capacity and as such has laid the foundations for the development of a non-hormonal male contraceptive.


          Hanne Mørck Nielsen´s research is focused on drug delivery of biotherapeutics, mainly peptides. Her work is interdisciplinary and involves designing and characterizing functional excipients and drug delivery systems and understanding their delivery propensity related to interactions with biobarriers such as mucus and epithelia, and how this translates to therapeutic responses. Membrane-interacting peptides, and in particular cell-penetrating peptides, their mode of action, and delivery efficiency have been investigated. Hanne Mørck Nielsen completed her PhD in Pharmaceutical Sciences on buccal drug delivery of peptides on research conducted at the Royal Danish School of Pharmacy, Denmark and Leiden/Amsterdam Center for Drug Research, the Netherlands. After a post doc at ETH Zürich, Switzerland working on cell-penetrating peptides, she was employed at the University of Copenhagen and in 2016 promoted to full Professor in Biopharmaceuticals – Drug Design and Delivery. She is Director of the BioDelivery Center and the Drug Delivery and Biophysics of Biopharmaceuticals group at Department of Pharmacy, University of Copenhagen.


          Meritxell Teixidó holds a PhD in Organic Chemistry from the University of Barcelona (UB) and an eMBA in Entrepreneurship, Innovation and International Business from UOC. At a scientific level, her field is the synthesis of peptides and the discovery of peptides capable of crossing biological barriers and she was responsible for this research line at the IRB Barcelona for more than 15 years, where she co-directed 10 doctoral theses, published more than 50 articles and participated in 7 patents.

          After dedicating more than 15 years to biomedical research at IRB Barcelona, trying to improve the arrival of drugs to the brain by crossing the blood-brain barrier that protects it. She decided to jump more barriers and be the CEO/CSO of Gate2Brain SL. in order to bring technology closer to patients, a challenge and an honor. Jumping barriers is perhaps the common thread that describes her, combining science and innovation with a new vision on leadership, for which she received the Spanish Woman Startup Award 2022 – Inspiration.


          Kaido Kurrikoff focuses his research on drug delivery methods, nucleic acid therapeutics, and nucleic acid diagnostics. His background from the PhD studies is Neuroscience and animal models for CNS-related pathologies. Currently, he is exploring the possibilities of developing CPP-based carrier systems for delivering macromolecular therapeutics. He is focused on development nucleic acid delivery methods through in vivo preclinical models, mainly using cancer gene therapy.


          Tamas A. Martinek was born in Szeged, Hungary, in 1973. After obtaining his MSc in Chemistry from University of Szeged, Hungary, in 1996, he earned his PhD degree at the same university in 2001 under the supervision of Ferenc Fülöp and with the guidance of Frank G. Riddell at the University of St. Andrews, UK. He is full professor and the head of the Department of Medical Chemistry, Albert Szent-Györgyi Medical School, University of Szeged. He started his independent career in the field of peptidic foldamers focusing on their controlled secondary and tertiary structures. He is currently active in the field of biomimetic self-organizing systems and their applications in drug discovery: endocytotic cell penetration, antimicrobial foldamers, modulation of protein-protein interactions, light-fueled peptidic replicators.


          Astrid Walrant did her PhD in Paris, at the Laboratoire des Biomolecules, Pierre et Marie Curie University, under the supervision of Isabel Alves and Sandrine Sagan, between 2008 and 2011. Her Ph.D. work focused on the analysis of peptide/membrane interactions in the context of cell-penetrating peptides.

          In 2012, Dr Walrant joined Jenny Gallop’s group at the Gurdon Institute, Cambridge University, as a postdoctoral research fellow. I worked on the regulation of actin polymerization by lipid membranes. My work focused on the regulatory role of certain phosphoinositides, membrane curvature, and curvature-inducing proteins.

          In 2014, Dr. Walrant came back to Paris and joined the Laboratoire des Biomolecules as Assistant Professor attached to the Chemistry Faculty. Her research focuses on the analysis of the mechanism of action of membrane-active peptides (cell-penetrating, antimicrobial, viral…) at a molecular level, using biophysical approaches.


          Ines Neundorf studied chemistry at the Universities of Freiburg and Leipzig and obtained her diploma in chemistry at the University of Leipzig in 2001. In 2003, she completed her doctorate in organic chemistry there. She then did her Habilitation in Leipzig in the group of Professor Dr. Annette Beck-Sickinger (Venia Legendi in Bioorganic Chemistry). In 2011, during the completion of her Habilitation, she accepted the offer of a junior professorship (with tenure track) in biochemistry at the University of Cologne’s Institute of Biochemistry. In 2016, she was tenured as W2 Professor of Biochemistry. Since 2022, she has been Vice-Dean for Equality, Diversity and Early-Career Researchers at the Faculty of Mathematics and Natural Sciences. She is a member of the University of Cologne’s Advisory Board for Equal Opportunities and since October 2023 she is Vice-Rector for Academic Career and Staff Development.
          Her main research interests are in the fields of bioactive peptides, such as: antimicrobial peptides, cell-penetrating peptides, organelle targeting sequences, peptide synthesis and modification, peptides in tumor diagnosis and therapy. Her research results have been published in numerous peer-reviewed journals, and she is co-author of >90 peer-reviewed publications and 4 book chapters. Ines Neundorf is an associate editor of Scientific Reports and since 2013, she has been a member of the Max-Bergmann-Kreis e.V., a network promoting research work in peptide chemistry in Germany, Switzerland and Austria.


          Taavi Lehto received his PhD in 2011 in Biomedical Engineering at the University of Tartu (Estonia). After post-doctoral stints at University of Montpellier with Prof. Bernard Lebleu, University of Munich with Prof. Ernst Wagner and Karolinska Institute with Prof. Edvard Smith/Prof. Samir EL Andaloussi, he moved back to his native Estonia in 2019 to start his own research group at the Institute of Technology at University of Tartu. His lab is focusing on the development of various peptidic/polymeric drug delivery systems for the delivery of nucleic acid-/RNA-based therapeutic modalities.


           

          Christian Widmann received his MSc in biology in 1986. He obtained his PhD at the Biochemistry Institute of the University of Lausanne in 1991 under the supervision of Giampietro Corradin. He then worked on the GLP1 receptor as a post-doctoral fellow in the laboratory of Bernard Thorens until 1995. Christian obtained a fellowship from the Swiss National Science Foundation in 1996 to move to the laboratory of Gary L. Johnson at the National Jewish Medical and Research Center in Denver, Colorado, where he worked as a research associate on MAPK pathways until 1998. In 1999, he moved back to Europe and started his own research group at the University Hospital in Lausanne. In 2002, he got an assistant professor position at the Department of Cell Biology and Morphology at the University of Lausanne.

          Since 2006, he is an associate professor at the Department of Physiology of the University of Lausanne (now Department of Biomedical Sciences). The first wave of his research was centered on the regulation of cellular stress and how a better understanding of these mechanisms at the molecular level could lead to the development of therapeutic compounds to treat various diseases such as cancer, microbial infections, and diabetes. The current focus of his laboratory is on the mechanisms of entry of cell permeable peptides


          We thank our sponsors

           

          Book of abstracts_23rd GFPP

          Book of abstracts GFPP23!

           

          (updated September 25, 2023)

           

          Our missions

          The French Peptide Society

          Our missions

          The French Group of Peptides and Proteins (GFPP) is a society funded in 1978 which brings together around 200 members who are de facto the participants in biennial congresses of the GFPP. It is administered by an executive commitee composed of twelve members elected during these congresses, as well as the French delegate at the European Peptide Society (EPS) who is elected every four years by the French EPS members.

          The missions of the GFPP are:

          1) to promote the development of research in the field of peptide and protein science.

          2) to stimulate the circulation of national and international scientific informations in these fields. With this in mind, the GFPP organizes its  congress every two years (4 to 5 days), short thematic meetings (1 to 3 days) and manages a mailing list.

          3) to participate in the training of young researchers, engineers and technicians from French laboratories. The GFPP regularly awards grants to: participate in international congresses in the field of peptides / proteins or fund inter-laboratory exchanges to disseminate new techniques and / or train young scientists in multidisciplinary approaches.

          Article submission for publication on GFPP website

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          You have been invited to prepare a GFPP Featured Article to be published on the GFPP website home page. This is a unique opportunity to promote your research and make your team more visible, given the number of visits GFPP website receives each day.

          Please follow carefully the guidelines as not doing so will considerably delay the publication of the Featured Article. The GFPP reserves the right to not publish the Featured Article if quality standards are not met.

          Pay particularly attention to:

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            Best poster communication awards

            GFPP23
            Best poster communication awards

            GFPP23 organized in September 2023 in Fournols (France) gave the opportunity to young talented people to present their research. The selection committee was impressed by the high quality of the poster presentations and has selected two awardees. We warmly  thank Genepep for sponsoring the award competition.

            GFPP23 awardees are Lucille Weiss (LIT, University of Strasbourg, France) and Francisco Tomas Ribeiro (DBS, University of Lausanne, Switzerland).

            GFPP23 Best oral communication awards

            GFPP23
            Best oral communication awards

            GFPP23 organized in September 2023 in Fournols (France) gave the opportunity to young talented people to present their latest research. The committee was impressed by the high quality of the oral presentations and has selected two awardees. We warmly thank Genepep for sponsoring the award competition.

            GFPP23 awardees are Benjamin Grain (CIIL, Lille, France) and Sonia Khemaissa (LBM, Sorbonne University, France).

            (more…)

            Aurélie Tasiemski

            Aurélie Tasiemski
            The environment shapes immune peptides

            Antimicrobial peptides (AMPs) play a key role in the external immunity of animals, offering an interesting model for studying the influence of the environment on the diversification and evolution of immune effectors. Alvinellacin (ALV), arenicin (ARE) and polaricin (POL, a novel AMP identified here), characterized from three marine worms inhabiting contrasted habitats (‘hot’ vents, temperate and polar respectively), possess a well conserved BRICHOS domain in their precursor molecule despite a profound amino acid and structural diversification of the C-terminal part containing the core active peptide.

            (more…)

            Peter Faller

            Peter Faller
            Transporting Cu into Cells with a Peptide

            In Alzheimer’s disease (AD) copper ions accumulates in amyloid plaques, a hallmark of this disease. This copper likely originating from intracellular sources. The Cu in amyloid plaques is bound to its main constituent, the peptide amyloid-β (Aβ). Cu-Aβ can catalyze the production of reactive oxygen species (ROS) in vitro and is thought to contribute to the oxidative stress observed in AD. The paper reports on the development of a novel Cu shuttle able to restore the Cu balance between intra- and extracellular Cu. (more…)

            Jean-Philippe Combier

            Jean-Philippe Combier
            Short peptides to replace chemicals in agronomy 

            The current agriculture main challenge is to maintain food production while facing multiple threats such as increasing world population, temperature increase, lack of agrochemicals due to health issues and uprising of weeds resistant to herbicides. Developing novel, alternative, and safe methods is hence of paramount importance. Here we show that complementary peptides (cPEPs) from any gene can be designed to target specifically plant coding genes. (more…)

            Gilles Subra (Zervas Award 2020)

            Gilles Subra (Zervas Award 2020)
            Moulding proteins with amino acids 

            Gilles Subra received the Zervas award from the EPS in 2022 during the 36th EPS meeting in Sitges (Spain). With this recent article, he shares with us some of the innovative work pursued in his team.

            MIP (molecular imprinted polymers) are prepared by polymerizing monomers around a template. After the removal of the template, the cavities in the material will be able to recognise and recapture selectively the molecule of interest. (more…)


            From The Journal of Peptide Science!

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            Other events sponsored by GFPP

            Other events sponsored by GFPP

             

            Year Meeting title City
            2022 7th International Symposium on Antimicrobial Peptides – AMP2022 Paris
            2022 Ecole thématique du GDR MuFoPAM PAMOMICS Roscoff
            2022 MBP 2022.  International Conference on Metal-Binding Peptides: Methodologies and Applications Nancy
            2021 2nd PEPPERSchool Virtual event
            2018 Pepperschool Carry-Le-Rouet
            2016 Ecole thématique GDR MuFoPam Beg Meil
            2015 Symposium Foldamères Bordeaux
            2013 Paris Foldamers 2013 Symposium (COST Action CM0803) Paris
            2012 Bordeaux 2012 Symposium on Foldamers (COST Action CM0803) Bordeaux
            2010 Congrès international d’endocrinologie Rouen

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              Past GFPP meetings

              Past GFPP meetings

              Year City Meeting number Website
              2025 23 Soon
              2023 Fournols 23 Website
              2022 Port-Leucate  22 Website
              2019 Amboise 21 Website
              2017 Arcachon 20 Website
              2015 Portbail 19 Website
              2013 Sète 18
              2011 Aussois 17
              2009 Albé 16
              2007 Dinard 15
              2005 Aussois 14
              2003 Biarritz 13
              2002 Aussois 12
              1999 Aussois 11
              1997 Montpellier 10: Fourth Forum on Peptides and Proteins
              1995 Aussois 9
              1993 Biarritz 8: Third Forum on Peptides
              1991 Aussois 7
              1988 Nancy 6: Second Forum on Peptides
              1986 Le Touquet 5
              1984 Montpellier 4: First Forum on Peptides
              1982 Chamerolles 3
              1980 Toulon 2
              1978 Pont-à-Mousson 1

               

              Our Sponsors

              Organizing & Scientific committees

              Organizing Committee

              Sonia Cantel

              Dr Sonia Cantel
              Institut des Biomolécules Max Mousseron
              IBMM, UMR 5247, Montpellier – France

              Steven Ballet
              Organic Chemistry Research Group
              OCRG, Vrije Universiteit, Brussel – Belgium

              Nicolas Inguimbert
              CRIOBE
              USR 3278, Perpignan – France

              Annemieke Madder
              Department of Organic and Macromolecular Chemistry
              Universiteit Gent, Gent – Belgium

              Scientific Committee

              Vincent Aucagne
              Centre de Biophysique Moléculaire (CBM, UPR 4301) Orléans

              Steven Ballet
              Organic Chemistry Research Group (OCRG, Vrije Universiteit Brussel) Brussel

              Frédéric Bihel
              Laboratoire d’innovation thérapeutique (UMR7200) Strasbourg

              Sonia Cantel
              Institut des Biomolécules Max Mousseron (IBMM, UMR 5247) Montpellier

              Florine Cavelier
              Institut des Biomolécules Max Mousseron (IBMM, UMR 5247) Montpellier

              Grégory Chaume
              Laboratoire de Chimie Biologique (LCB, EA 4505) Cergy-Pontoise

              Sophie Faure
              Institut de Chimie de Clermont-Ferrand (ICCF, UMR 6296) Clermond-Ferrand

              Elisabeth Garanger
              Laboratoire de Chimie des Polymères Organiques (LCPO, UMR 5629) Bordeaux

              Matthieu Giraud
              CordenPharma International, Switzerland

              Nicolas Inguimbert
              Centre de Recherche et Observatoire de l’Environnement (CRIOBE, USR 3278) Perpignan

              Olivier Lequin
              Laboratoire des Biomolécules (UMR 7203, Paris)

              Annemieke Madder
              Department of Organic and Macromolecular Chemistry, Universiteit Gent, Gent

              Françoise Ochsenbein
              CEA Saclay (IBITEC-S/SB2SM/LBSR) Gif sur Yvette

              Isabelle Segalas-Milazzo
              COBRA (UMR 6014), Rouen

              Olivier Sénèque
              Laboratoire de Chimie et Biologie des Métaux (UMR 5249, CEA) Grenoble

              Dirk Tourwé
              Organic Chemistry Research Group (OCRG, Vrije Universiteit Brussel) Brussel

              Compliance leader, Corden Pharma Brussels

              The Compliance Leader will be working as part of the Corden Pharma Brussels Quality Assurance Department and ensure that the products are manufactured, stored and packaged in accordance with cGMP regulation. The Compliance Leader will be working as part of the Quality Unit on site ensuring products are manufactured, stored and packaged in accordance with the cGMP. Under the direction of the Head of Quality, he/she will be in charge to improve continuously the Quality system regarding the cGMP requirements. He/She will be a QA support in case of quality issues and problem solving techniques to assure the successful outcomes of company and external Health Authority. He/She will be in direct contact with our customer in case of qualification audit, QA complaint issues and other quality topics. The Compliance Leader is reporting to the Head of Quality.

              1561112606-Compliance-Leader-2019.pdf

              MedChem 2019 – Peptide Drug Discovery: a Niche Area ?

              November 22, 2019 | Brussels, Belgium

              The objective of the event is to discuss the multifaceted therapeutic potential of peptides. Topics such as peptidomimetics and macrocycles, protein-protein interactions, peptide shuttles, chemical ligation and main aspects of peptide synthesis will be tackled.

              The confirmed speakers are:

              Linkers for Peptide Conjugation
              Prof. Fernando Albericio, University of Kwazulu-Natal, South Africa
              Synthetic Immune System Engagers – a Peptide-based Approach to Immune-oncology
              Prof. Christian Becker, University of Vienna, Austria
              From Structure to Function: Peptide Recognition at G Protein-coupled Receptors
              Dr Anette Kaiser, University of Leipzig, Germany
              Macrocyclization as an Enabling Tool Toward Novel Peptide Drug Candidates
              Prof. Eric Marsault, University of Sherbrooke, Canada
              Targeting Receptor Complexes: A New Dimension in Drug Discovery
              Prof. Kristian Strømgaard, University of Copenhagen, Denmark
              Gate2Brain, Opening the Gate to CNS Therapies
              Dr Meritxell Teixido, Institute for Research in Biomedicine, Spain

              All participants are invited to submit abstracts for scientific communications. Out of the submitted proposals, 3 Oral Communications will be selected. The other accepted abstracts will get the opportunity to be presented as Posters.

              Submission deadline: October 10, 2019

              More information is available on www.medchem.be

              Lei LIU

              Department of Chemistry Tsinghua University, Beijing, China

               « Title to be announced »

              Website

              Closing lecture

              Please find below the finalized speaker list, after a couple of last minute changes.

              Alesia TIETZE

              Department of Chemistry and Molecular Biology University of Gothenburg, Göteborg, Sweden

               « Chemical synthesis of membrane-associated peptides: studies on influenza virus B protein BM2 »

              Website

              Biography and abstract

              Birgit WILTSCHI

              Synthetic Biology Group, ACIB – Austrian Centre of Industrial Biotechnology, Graz , Austria

              « Engineering of proteins with non-canonical amino acids in industrial biotechnology »

              Website

              Biography and abstract

               

               

               

               

              Prof. Daniel N. WILSON

              Institute for Biochemistry and Molecular Biology, University of Hamburg  ―  Germany. “Proline-rich antimicrobial peptides targeting protein synthesis” (Abstract) Website

              Mimoun AYOUB

              Bord member
              MImoun AyoubBruehlfeldweg 14 – 8112 Otelfingen, Switzerland
              Phone: +41 79 937 5302
              email

              Welcome

              We are pleased to announce that the next meeting of the French Peptides and Proteins Group will be held in Amboise (Région Centre-Val-de-Loire), from Sunday 12th to Thursday 16th May 2019, in the beautiful and historic Loire valley area.

              Note that 2019 will be the 41th anniversary of the creation of the GFPP and also the 500th anniversary of the death of Leonardo Da Vinci, who spent his last years in Amboise, in the Chateau du Clos-Lucé, located a few kilometers away from the conference center.

              We have gathered a rich program of plenary speakers, spanning cutting-edge themes in the peptide and protein science field.

              A large part of the program will be dedicated to oral communications from young scientists. As usual, around 20 grants will be attributed to young investigators to cover their registration fees.

              The official language of the congress is English. For any enquiry, please contact us.

              Looking forward to seeing you in Amboise !

              The GFPP board members

              How to get to Amboise

              • The 21th GFPP meeting will be held at the Villa Bellagio resort, located 3 km away from the town center.
              • By car: Motorway A10 then D31 (19 km) /  motorway A85 then D31 (15 km).
              • OpenStreetMap link
              • GPS: 47.3918,1.0066
              • By plane: Paris airports then train.
              • The Amboise train station is well deserved including frequent connexions from Tours TGV station and direct trains from Paris (https://en.oui.sncf/en/) .
              Bus shuttles are scheduled for the trains arriving at Amboise at 17h21 and 17h38 on Sunday, and for those departing at 13h46, 13h55 and 14h23 on Thursday, so please book your tickets in accordance. Important notice: the SNCF website does not propose all the possible combinations of trains, and it can be necessary to do two separate searches:  (1) your town -> Paris then (2) Paris-> Amboise.

              Taxi companies in Amboise

              Registration to the 21st GFPP

              Registrations are now closed

              Key Dates:

              1st November 2018 : opening of registration and abstract submission

              18th January 2019 : deadline for oral communications submissions and young researchers bursary applications.

              1st March 2019 : end of early bird fees for registration.

              15th March 2019 : deadline for poster communication abstract submission. 1st April 2019 : end of registration.

              12th May 2019, 6:30 pm : official opening of the congress

              Registration fees includes :

              •Access to all scientific sessions • Abstract book • Full board accomodation (lodging, breakfast, lunch, dinner, coffee breaks) at the Villa Bellagio resort in Amboise • Excursions on Tuesday afternoon
              • Welcome reception and gala dinner

              Note that the above-mentionned fees apply for twin room accomodation (academic or private company delegates) or triple rooms (students/postdoc). A single room option will be available (not applicable for students/postdocs) at a supplementary cost of 150 € for academic delegate and of 130 € for private company delegate.

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